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Surgical resection, radiotherapy and percutaneous thermal ablation for treatment of stage 1 non-small cell lung cancer: protocol for a systematic review and network meta-analysis
Introduction Non-small cell lung cancer (NSCLC) makes up the majority of lung cancer cases. Currently, surgical resection is the gold standard of treatment. However, as patients are becoming medically more complex presenting with advanced disease, minimally invasive image-guided percutaneous ablations are gaining popularity. Therefore, comparison of surgical, ablative and second-line external beam therapies will help clinicians, as management of NSCLC changes. We will conduct a meta-analysis, reviewing literature investigating these therapies in adult patients diagnosed with stage 1 NSCLC, with neither hilar nor mediastina...
Source: BMJ Open - June 16, 2022 Category: General Medicine Authors: Chockalingam, A., Konstantinidis, M., Koo, B., Moon, J. T., Tran, A., Nourouzpour, S., Lawson, E., Fox, K., Habibollahi, P., Odisio, B., Loya, M., Bassir, A., Nezami, N. Tags: Open access, Oncology Source Type: research

A systematic review of interventions to recognise, refer and diagnose patients with lung cancer symptoms
NPJ Prim Care Respir Med. 2022 Oct 18;32(1):42. doi: 10.1038/s41533-022-00312-9.ABSTRACTPatients with lung cancer (LC) often experience delay between symptom onset and treatment. Primary healthcare professionals (HCPs) can help facilitate early diagnosis of LC through recognising early signs and symptoms and making appropriate referrals. This systematic review describes the effect of interventions aimed at helping HCPs recognise and refer individuals with symptoms suggestive of LC. Seven studies were synthesised narratively. Outcomes were categorised into: Diagnostic intervals; referral and diagnosis patterns; stage distri...
Source: Cancer Control - October 18, 2022 Category: Cancer & Oncology Authors: Mohamad M Saab Megan McCarthy Michelle O'Driscoll Laura J Sahm Patricia Leahy-Warren Brendan Noonan Serena FitzGerald Maria O'Malley Noreen Lyons Heather E Burns Una Kennedy Áine Lyng Josephine Hegarty Source Type: research

Cuba Has Made At Least 3 Major Medical Innovations That We Need
By most measures, the United States' business-friendly environment has proven to be fertile for medical innovation. Compared to other countries, America has filed the most patents in the life sciences, is conducting most of the world's clinical trials and has published the most biomedical research. That's what makes the medical prominence of Cuba all the more surprising to those who view a free market as an essential driver of scientific discovery. Cuba is very poor, and yet the country has some of the healthiest, most long-lived residents in the world -- as well as a medical invention or two that could run circl...
Source: Science - The Huffington Post - March 15, 2016 Category: Science Source Type: news

Navigate Transition to Value-Based Care, Payment Models With ACR 2016 Quality and Safety Sessions
Washington, DC  — ACR 2016® quality and safety sessions help radiology professionals enhance and strengthen their practices, providing specific strategies and tools to improve patient care and transition from volume- to value-based payment models. “ACR 2016 quality and safety sessions focus on topics that patients care about, such as radiation dose optimization and methods to increase patient satisfaction,” said Cheri Canon, MD, FACR, chair of the ACR 2016 Program Committee. “Radiology professionals must adapt to new alternative payment models, and ACR 2016 sessions help attendees navigat...
Source: American College of Radiology - February 17, 2016 Category: Radiology Source Type: news

Physicians ’ Responsibilities in Shared Decision Making for Lung Cancer Screening—Reply
In Reply We thank De Allie and colleagues for their comments on our article. We agree that many primary care physicians (PCPs) lack skills in shared decision making (SDM), particularly SDM using decision aids. This lack should be ameliorated by incorporation of education on decision aids into undergraduate, postgraduate, and continuing medical education. Formal SDM with decision aids is one method to promote patient-centered medicine, as are good listening skills and sufficient time budgeted for clinical encounters to create space for patients to express their values and preferences.
Source: JAMA Internal Medicine - July 1, 2019 Category: Internal Medicine Source Type: research

Abstract A59: Providing care for LGBTQ individuals with cancer: A call for education and training
Conclusions: Survey results indicate that oncology providers in specialties where LGBTQ patients may be disproportionately affected are accepting of LGBTQ individuals and acknowledge the existence of unique needs for this population, yet are largely unaware of specific health behaviors and risk factors of, and best practices regarding, this population. This study also highlights the potential need for improved LGBTQ-related content in health professional school curricula, as well as for continuing education and training for providers that addresses the care of LGBTQ patient populations.Citation Format: Christina Tamargo, J...
Source: Cancer Epidemiology Biomarkers and Prevention - April 14, 2016 Category: Cancer & Oncology Authors: Tamargo, C., Sanchez, J. A., Sutton, S. K., Kanetsky, P. A., Simmons, V. N., Vadaparampil, S. T., Schabath, M. B., Quinn, G. P. Tags: Health Education: Poster Presentations - Proffered Abstracts Source Type: research

Q&A: Dr. John Mazziotta on the future of UCLA’s medical school and health system
Earlier in his life, Dr. John C. Mazziotta thought about becoming an architect. With a keen eye for form and function, he would apply his skills to the construction of great buildings. Instead, he chose medicine. Now, after more than 30 years at UCLA — where he has been chair of the department of neurology, an associate vice chancellor and executive vice dean, and founding director of the Ahmanson-Lovelace Brain Mapping Center — that style of visual thinking will serve him well in his new roles as vice chancellor for UCLA Health Sciences, dean of the David Geffen School of Medicine at UCLA and CEO of UCLA Health. “Th...
Source: UCLA Newsroom: Health Sciences - May 27, 2015 Category: Universities & Medical Training Source Type: news

Continuing EGFR-TKI treatment in combination with super-selective arterial infusion chemotherapy beyond disease progression for patients with advanced EGFR-mutant non-small cell lung cancer
This study evaluated the efficacy and safety of continuing EGFR-TKI therapy concurrently with arterial infusion chemotherapy in 6 patients (median age 55.9 years) with advanced EGFR-mutant non-small cell lung cancer (NSCLC) who had a locally progressive, centrally located lung lesion after EGFR-TKI therapy. The patients received a super-selective arterial infusion of docetaxel (75 mg/m2) every 28 days concurrently with EGFR-TKI therapy until further progressive disease (PD) or unacceptable adverse effects (AEs) occurred. Treatment outcomes were assessed via progression-free survival (PFS) times (PFS-1: time to PD after ...
Source: Medical Oncology - October 23, 2015 Category: Cancer & Oncology Source Type: research

Patient-based benefit-risk assessment of medicines: development, refinement, and validation of a content search strategy to retrieve relevant studies
J Med Libr Assoc. 2022 Apr 1;110(2):185-204. doi: 10.5195/jmla.2022.1306.ABSTRACTINTRODUCTION: Poor indexing and inconsistent use of terms and keywords may prevent efficient retrieval of studies on the patient-based benefit-risk assessment (BRA) of medicines. We aimed to develop and validate an objectively derived content search strategy containing generic search terms that can be adapted for any search for evidence on patient-based BRA of medicines for any therapeutic area.METHODS: We used a robust multistep process to develop and validate the content search strategy: (1) we developed a bank of search terms derived from s...
Source: Journal of the Medical Library Association : JMLA - April 20, 2022 Category: Databases & Libraries Authors: Hiba El Masri Treasure M McGuire Christine Dalais Mieke van Driel Helen Benham Samantha A Hollingworth Source Type: research